Which description best matches the corneal infiltrate seen in contact lens peripheral ulcer (CLPU)?

Which description best matches the corneal infiltrate seen in contact lens peripheral ulcer (CLPU)?

• A. Irregular, diffuse, grayish infiltrate centrally
• B. Circular, well-defined, dense white focal corneal infiltrate located peripherally
• C. Small punctate infiltrates scattered on the cornea
• D. Large thinned cornea with stromal melt near the limbus

Answer: (B)

The infiltrate seen in contact lens peripheral ulcer is best described as a circular, well-defined, dense white focal corneal infiltrate located peripherally near the limbus. This discrete, peripheral lesion reflects a localized inflammatory reaction related to contact lens wear, rather than a widespread or central infectious process. Other patterns—irregular diffuse central infiltrates, small scattered punctate infiltrates, or a thinned cornea with stromal melt—fit different conditions or more severe keratopathy, not the typical presentation of CLPU.

The infiltrate seen in contact lens peripheral ulcer is best described as a circular, well-defined, dense white focal corneal infiltrate located peripherally near the limbus. This discrete, peripheral lesion reflects a localized inflammatory reaction related to contact lens wear, rather than a widespread or central infectious process. Other patterns—irregular diffuse central infiltrates, small scattered punctate infiltrates, or a thinned cornea with stromal melt—fit different conditions or more severe keratopathy, not the typical presentation of CLPU.